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Blood pressure determinants of cerebral white matter hyperintensities and microstructural injury: UK Biobank cohort study

Abstract:

Small vessel disease and related stroke and dementia risks are linked to aging and hypertension, but it is unclear whether the pulsatile or steady blood pressure (BP) component is more important for the development of macrostructural hyperintensities and microstructural white matter damage. This was a cross-sectional analysis of the UK Biobank cohort study of community-based adults from 22 UK centers. Linear associations were determined between neuroimaging markers (white matter hyperintensit...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/HYPERTENSIONAHA.121.17403

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
American Heart Association
Journal:
Hypertension More from this journal
Volume:
78
Issue:
2
Pages:
532–539
Publication date:
2021-06-01
Acceptance date:
2021-04-28
DOI:
EISSN:
1524-4563
ISSN:
0194-911X

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