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Inert-gas washout and forced oscillation technique show sensitivity to the degree of regionalisation of bronchoconstriction

Abstract:
The Multiple-breath washout (MBW) and Forced Oscillation Technique (FOT) are both experiencing increased uptake as clinical measures of lung function and airway constriction. However, due to the complex nature of test outputs, there is still uncertainty about exactly how test indices respond to specific types of bronchoconstriction. Through the analysis of hundreds of bronchoconstriction scenarios, we investigated the sensitivity of MBW and FOT indices to the degree of regionalisation of airway constriction.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Institution:
University of Oxford
Department:
New College
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Computer Science
Role:
Author
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Funding agency for:
Foy, B
Publisher:
American Thoracic Society Publisher's website
Journal:
Proceedings of the American Thoracic Society Journal website
Volume:
2017
Issue:
195
Pages:
A4881
Publication date:
2017-05-05
Acceptance date:
2017-01-12
ISSN:
1943-5665 and 1546-3222
Pubs id:
pubs:681663
URN:
uri:0d4a2a06-b7f7-4b61-9706-f2c4cf757598
UUID:
uuid:0d4a2a06-b7f7-4b61-9706-f2c4cf757598
Local pid:
pubs:681663
Paper number:
195

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