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Journal article

Variation in the ICAM1 gene is not associated with severe malaria phenotypes.

Abstract:

Evidence from autopsy and in vitro binding studies suggests that adhesion of erythrocytes infected with Plasmodium falciparum to the human host intercellular adhesion molecule (ICAM)-1 receptor is important in the pathogenesis of severe malaria. Previous association studies between polymorphisms in the ICAM1 gene and susceptibility to severe malarial phenotypes have been inconclusive and often contradictory. We performed genetic association studies with 15 single nucleotide polymorphisms (SNP...

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Publication status:
Published

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Publisher copy:
10.1038/gene.2008.38

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Journal:
Genes and immunity More from this journal
Volume:
9
Issue:
5
Pages:
462-469
Publication date:
2008-07-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Language:
English
Keywords:
Pubs id:
pubs:34259
UUID:
uuid:0d3107f2-2e6f-4f6c-a8c4-5f1dcd0de76c
Local pid:
pubs:34259
Source identifiers:
34259
Deposit date:
2012-12-19

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