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Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections

Abstract:

A xenotropic murine leukemia virus-related virus (XMRV) has recently been reported in association with prostate cancer and chronic fatigue syndrome, with a prevalence of up to 3.7% in the healthy population. We looked for XMRV in 230 patients with human immunodeficiency virus type 1 or hepatitis C infection. XMRV was undetectable in plasma or peripheral blood mononuclear cells by polymerase chain reaction targeting XMRV gag or env. T cell responses to XMRV Gag were undetectable in peripheral ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1086/657167

Authors


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Department:
Default/Not Applicable
Flanagan, P More by this author
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Department:
Oxford, MSD, NDM, Experimental Medicine
Robinson, N More by this author
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Wellcome Trust More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Infectious Diseases Journal website
Volume:
202
Issue:
10
Publication date:
2010-11-15
Acceptance date:
2010-07-29
DOI:
ISSN:
0022-1899 and 1537-6613
Pubs id:
pubs:89587
URN:
uri:0d245a98-8d72-4afc-a142-20eb798bd842
UUID:
0d245a98-8d72-4afc-a142-20eb798bd842
Local pid:
pubs:89587

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