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Agreement between ELISA and plaque reduction neutralisation assay in Detection of respiratory syncytial virus specific antibodies in a birth Cohort from Kilifi, coastal Kenya

Abstract:

Background: Severe disease associated with respiratory syncytial virus (RSV) infection occurs predominantly among infants under 6 months of age. Vaccines for prevention are in clinical development. Assessment of the vaccine effectiveness in large epidemiological studies requires serological assays which are rapid, economical and standardised between laboratories. The objective of this study was to assess the agreement between two enzyme linked immunosorbent assays (ELISA) and the plaque reduc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0001-7215-6539
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Institution:
University of Oxford
Division:
SE-Other
Department:
External
Role:
Author
ORCID:
0000-0002-8364-6063
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Role:
Author
ORCID:
0000-0001-9419-7155
Publisher:
F1000Research
Journal:
Wellcome Open Research More from this journal
Volume:
4
Issue:
33
Publication date:
2019-02-18
Acceptance date:
2019-02-18
DOI:
EISSN:
2398-502X
ISSN:
2398-502X
Pmid:
30906883
Language:
English
Pubs id:
pubs:987350
UUID:
uuid:0cfa2a96-b060-4d63-9c23-17832afb8d13
Local pid:
pubs:987350
Source identifiers:
987350
Deposit date:
2019-04-04

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