Journal article icon

Journal article

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Abstract:

The volume of the lateral ventricles (LV) increases with age and their abnormal enlargement is a key feature of several neurological and psychiatric diseases. Although lateral ventricular volume is heritable, a comprehensive investigation of its genetic determinants is lacking. In this meta-analysis of genome-wide association studies of 23,533 healthy middle-aged to elderly individuals from 26 population-based cohorts, we identify 7 genetic loci associated with LV volume. These loci map to ch...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

Actions


Access Document


Files:
Publisher copy:
10.1038/s41467-018-06234-w

Authors


More by this author
Role:
Author
ORCID:
0000-0001-5744-0232
More by this author
Role:
Author
ORCID:
0000-0003-3687-2508
More by this author
Role:
Author
ORCID:
0000-0002-3658-1375
More by this author
Role:
Author
ORCID:
0000-0003-1942-5845
Expand authors...
Expand funders...
Publisher:
Springer Nature Publisher's website
Journal:
Nature Communications Journal website
Volume:
9
Pages:
3945
Publication date:
2018-09-26
Acceptance date:
2018-08-08
DOI:
EISSN:
2041-1723
Pubs id:
pubs:922161
URN:
uri:0cab941f-86c5-47fb-a0c2-a11fd868e1e0
UUID:
uuid:0cab941f-86c5-47fb-a0c2-a11fd868e1e0
Local pid:
pubs:922161
Language:
English
Keywords:

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP