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Reactive and pre-emptive vaccination strategies to control hepatitis E infection in emergency and refugee settings: a modelling study

Abstract:
Background Hepatitis E Virus (HEV) is the leading cause of acute viral hepatitis globally. Symptomatic infection is associated with case fatality rates of ~20% in pregnant women and it is estimated to account for ~10,000 annual pregnancy-related deaths in southern Asia alone. Recently, large and well-documented outbreaks with high mortality have occurred in displaced population camps in Sudan, Uganda and South Sudan. However, the epidemiology of HEV is poorly defined, and the... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pntd.0006807

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-9445-7217
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More from this funder
Funding agency for:
Cooper, B
Grant:
MR/ K006924/1
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Grant:
Mahidol University-Oxford Tropical Medicine Research Programme
106698/Z/14/Z
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
12
Issue:
9
Pages:
e0006807
Publication date:
2018-09-25
Acceptance date:
2018-09-03
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Pubs id:
pubs:911901
UUID:
uuid:0caadec0-bf9b-4fba-9664-275baa227ab4
Local pid:
pubs:911901
Source identifiers:
911901
Deposit date:
2018-09-04

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