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Peripheral Serotonin 1B receptor transcription predicts the effect of acute Tryptophan depletion on risky decision-making

Abstract:
Background: The effects of acute tryptophan depletion on human decision-making suggest that serotonin modulates the processing of rewards and punishments. However, few studies have assessed which of the many types of serotonin receptors are responsible. Methods: Using a within-subject, double-blind, sham-controlled design in 26 subjects, we examined whether individual differences in serotonin system gene transcription, measured in peripheral blood, predicte... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ijnp/pyw075

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Publisher:
Oxford University Press
Journal:
International Journal of Neuropsychopharmacology More from this journal
Volume:
20
Issue:
1
Pages:
58–66
Publication date:
2016-09-16
Acceptance date:
2016-08-13
DOI:
EISSN:
1469-5111
ISSN:
1461-1457
Keywords:
Pubs id:
pubs:681379
UUID:
uuid:0c88bfd2-08c5-439c-9d0b-8477ecce5a76
Local pid:
pubs:681379
Source identifiers:
681379
Deposit date:
2018-09-03

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