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Chloramphenicol pharmacokinetics in African children with severe malaria.

Abstract:

The objective of this study was to determine if the current dosage regimen for chloramphenicol CAP administered to children with severe malaria SM for presumptive treatment of concomitant bacterial meningitis achieves steady state plasma CAP concentrations within the reported therapeutic range of 10-25 mg/l. Fifteen children (11 male, 4 female) with a median age of 45 months (range: 10-108 months) and having SM, were administered multiple intravenous doses (25 mg/kg, 6 hourly for 72 h) of chl...

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Publication status:
Published

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Publisher copy:
10.1093/tropej/fmi082
Journal:
Journal of tropical pediatrics More from this journal
Volume:
52
Issue:
4
Pages:
239-243
Publication date:
2006-08-01
DOI:
EISSN:
1465-3664
ISSN:
0142-6338
Language:
English
Keywords:
Pubs id:
pubs:185630
UUID:
uuid:0c3ff88c-34c3-46b5-bc34-24428da8428f
Local pid:
pubs:185630
Source identifiers:
185630
Deposit date:
2012-12-19

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