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Journal article

Optimal quantification of contact inhibition in cell populations

Abstract:

Contact inhibition refers to a reduction in the rate of cell migration and/or cell proliferation in regions of high cell density. Under normal conditions, contact inhibition is associated with the proper functioning tissues, whereas abnormal regulation of contact inhibition is associated with pathological conditions, such as tumor spreading. Unfortunately, standard mathematical modeling practices mask the importance of parameters that control contact inhibition through scaling arguments. Furt...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bpj.2017.09.016

Authors


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Institution:
University of Oxford
Oxford college:
St Hugh's College
Role:
Author
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Funding agency for:
Baker, R
Grant:
Leverhulme Research Fellowship
More from this funder
Funding agency for:
Baker, R
Grant:
Leverhulme Research Fellowship
Publisher:
Cell Press Publisher's website
Journal:
Biophysical Journal Journal website
Volume:
113
Issue:
9
Pages:
1920-1924
Publication date:
2017-10-13
Acceptance date:
2017-09-15
DOI:
ISSN:
0006-3495
Keywords:
Pubs id:
pubs:730582
UUID:
uuid:0c26b49b-2b09-42e4-9e5b-b2f300c4c470
Local pid:
pubs:730582
Source identifiers:
730582
Deposit date:
2017-10-02

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