Journal article
Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning
- Abstract:
-
Semaphorin ligands and their plexin receptors are one of the major cell guidance factors that trigger localised changes in the cytoskeleton. Binding of semaphorin homodimer to plexin brings two plexins in close proximity which is a prerequisite for plexin signalling. This model appears to be too simplistic to explain the complexity and functional versatility of these molecules. Here, we determine crystal structures for all members of Drosophila class 1 and 2 semaphorins. Unlike previously rep...
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- Publication status:
- Accepted
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Communications Journal website
- Volume:
- 10
- Issue:
- 2019
- Article number:
- 3691
- Publication date:
- 2019-08-15
- Acceptance date:
- 2019-07-30
- DOI:
- ISSN:
-
2041-1723
Item Description
- Pubs id:
-
pubs:1036195
- UUID:
-
uuid:0c16a563-d1ce-462d-b578-efbb47249886
- Local pid:
- pubs:1036195
- Source identifiers:
-
1036195
- Deposit date:
- 2019-07-30
Terms of use
- Copyright holder:
- Rozbesky et al.
- Copyright date:
- 2019
- Notes:
- © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License
- Licence:
- CC Attribution (CC BY)
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