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PRDM9 diversity at fine geographical scale reveals contrasting evolutionary patterns and functional constraints in natural populations of house mice

Abstract:

One of the major challenges in evolutionary biology is the identification of the genetic basis of postzygotic reproductive isolation. Given its pivotal role in this process, here we explore the drivers that may account for the evolutionary dynamics of the PRDM9 gene between continental and island systems of chromosomal variation in house mice. Using a dataset of nearly 400 wild-caught mice of Robertsonian systems we identify the extent of PRDM9 diversity in natural house mouse populations, de...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/molbev/msz091

Authors


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Role:
Author
ORCID:
0000-0002-8264-9262
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
BDI-NDM
Department:
Unknown
Role:
Author
Publisher:
Oxford University Press
Journal:
Molecular Biology and Evolution More from this journal
Volume:
36
Issue:
8
Pages:
1686-1700
Publication date:
2019-04-19
Acceptance date:
2019-04-08
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
Pmid:
31004162
Language:
English
Keywords:
Pubs id:
pubs:995790
UUID:
uuid:0b9d7905-2f56-4de0-b32e-6e5902e06ced
Local pid:
pubs:995790
Source identifiers:
995790
Deposit date:
2019-05-10

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