Journal article
Clonal haematopoiesis and risk of acute myeloid leukemia
- Abstract:
-
Nearly all adults harbor acute myeloid leukemia-related clonal hematopoietic mutations at a variant allele fraction of ≥0.0001, yet relatively few develop hematologic malignancies. We conducted a nested analysis in the Nurses' Health Study and Health Professionals Follow-Up Study blood subcohorts, with up to 22 years of follow-up, to investigate associations of clonal mutations of ≥0.0001 allele frequency with future risk of acute myeloid leukemia. We identified 35 cases with acute myeloid le...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Ferrata Storti Foundation Publisher's website
- Journal:
- Haematologica Journal website
- Volume:
- 104
- Issue:
- 12
- Pages:
- 2410-2417
- Publication date:
- 2019-04-19
- Acceptance date:
- 2019-04-16
- DOI:
- EISSN:
-
1592-8721
- ISSN:
-
0390-6078
Item Description
- Language:
- English
- Pubs id:
-
pubs:993822
- UUID:
-
uuid:0b8e253e-e539-4ee3-83aa-c86c374eb8cd
- Local pid:
- pubs:993822
- Source identifiers:
-
993822
- Deposit date:
- 2019-04-24
Terms of use
- Copyright holder:
- Ferrata Storti Foundation
- Copyright date:
- 2019
- Notes:
- Copyright © 2019, Ferrata Storti Foundation. Material published in Haematologica is covered by copyright. All rights are reserved to the Ferrata Storti Foundation. Use of published material is allowed under the following terms and conditions: https://creativecommons.org/licenses/by-nc/4.0/legalcode. Copies of published material are allowed for personal or internal use. Sharing published material for non-commercial purposes is subject to the following conditions: https://creativecommons.org/licenses/by-nc/4.0/legalcode, sect. 3. Reproducing and sharing published material for commercial purposes is not allowed without permission in writing from the publisher.
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