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Journal article

Genome-Wide analysis of left ventricular image-derived phenotypes identifies fourteen loci associated with cardiac morphogenesis and heart failure development

Abstract:

Background: The genetic basis of left ventricular (LV) image-derived phenotypes, which play a vital role in the diagnosis, management, and risk stratification of cardiovascular diseases, is unclear at present.
Methods: The LV parameters were measured from the cardiovascular magnetic resonance studies of the UK Biobank. Genotyping was done using Affymetrix arrays, augmented by imputation. We performed genome-wide association studies of 6 LV traits—LV ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
American Heart Association
Journal:
Circulation More from this journal
Volume:
140
Issue:
16
Pages:
1318-1330
Publication date:
2019-09-25
Acceptance date:
2019-08-21
DOI:
EISSN:
1524-4539
ISSN:
0009-7322
Pmid:
31554410
Language:
English
Keywords:
Pubs id:
pubs:1060825
UUID:
uuid:0b719360-08c8-42c2-a1d1-efd12d51e8f4
Local pid:
pubs:1060825
Source identifiers:
1060825
Deposit date:
2019-10-22

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