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Journal article

18 F-fluoromisonidazole uptake in advanced stage non-small cell lung cancer: A voxel-by-voxel PET kinetics study.

Abstract:

Purpose

The aim of this study was to determine the relative abilities of compartment models to describe time-courses of 18F-fluoromisonidazole (FMISO) uptake in tumor voxels of patients with non-small cell lung cancer (NSCLC) imaged using dynamic positron emission tomography. Also to use fits of the best-performing model to investigate changes in fitted rate-constants with distance from the tumor edge.

Methods

Reversible and irreversible two- and three-tissue co...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/mp.12416

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
ORCID:
0000-0002-6880-5687
Macpherson, RE More by this author
Hackett, SL More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
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National Institute for Health Research More from this funder
Oxford Experimental Cancer Medicine Centre More from this funder
Oxford Cancer Imaging Centre More from this funder
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Publisher:
Wiley Publisher's website
Journal:
Medical Physics Journal website
Volume:
44
Issue:
9
Pages:
4665-4676
Publication date:
2017-07-05
Acceptance date:
2017-06-23
DOI:
EISSN:
2473-4209
ISSN:
0094-2405
Pubs id:
pubs:702294
URN:
uri:0b32512b-a9d0-4cc9-af82-a1cefb8e94a2
UUID:
uuid:0b32512b-a9d0-4cc9-af82-a1cefb8e94a2
Local pid:
pubs:702294

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