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The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs

Abstract:

RNA-binding proteins (RBPs) exert a broad range of biological functions. To explore the scope of RBPs across eukaryotic evolution, we determined the in vivo RBP repertoire of the yeast Saccharomyces cerevisiae and identified 678 RBPs from yeast and additionally 729 RBPs from human hepatocytic HuH-7 cells. Combined analyses of these and recently published data sets define the core RBP repertoire conserved from yeast to man. Conserved RBPs harbour defined repetitive motifs within disordered reg...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/ncomms10127

Authors


Beckmann, BM More by this author
Fischer, B More by this author
Castello, A More by this author
Eichelbaum, K More by this author
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Publisher:
Nature Publications Publisher's website
Journal:
Nature Communications Journal website
Volume:
6
Pages:
Article 10127
Publication date:
2015-12-03
Acceptance date:
2015-11-05
DOI:
ISSN:
2041-1723
Pubs id:
pubs:581717
URN:
uri:0b30a5ed-69ac-44d9-b33f-cac1d3d2cd21
UUID:
uuid:0b30a5ed-69ac-44d9-b33f-cac1d3d2cd21
Local pid:
pubs:581717

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