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Gateway to the Golgi: Molecular mechanisms of nucleotide sugar transporters

Abstract:

The Golgi apparatus plays a central role in the secretory pathway as a hub for posttranslational modification, protein sorting and quality control. To date, there is little structural or biochemical information concerning the function of transporters that reside within this organelle. The SLC35 family of nucleotide sugar transporters link the synthesis of activated sugar molecules and sulfate in the cytoplasm, with the luminal transferases that catalyse their attachment to proteins and lipids...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.sbi.2019.03.019

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Christ Church
Role:
Author
ORCID:
0000-0001-7432-2270
Publisher:
Elsevier
Journal:
Current Opinion in Structural Biology More from this journal
Volume:
57
Pages:
127-134
Publication date:
2019-04-15
DOI:
EISSN:
1879-033X
ISSN:
0959-440X
Pmid:
30999236
Language:
English
Keywords:
Pubs id:
pubs:994933
UUID:
uuid:0b205531-ce4c-4a80-84f5-98d9f61d48f1
Local pid:
pubs:994933
Source identifiers:
994933
Deposit date:
2019-06-10

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