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Influence of high intensity focused ultrasound on the microstructure and c-di-GMP signaling of Pseudomonas aeruginosa biofilms

Abstract:

Bacterial biofilms are typically more tolerant to antimicrobials compared to bacteria in the planktonic phase and therefore require alternative treatment approaches. Mechanical biofilm disruption from ultrasound may be such an alternative by circumventing rapid biofilm adaptation to antimicrobial agents. Although ultrasound facilitates biofilm dispersal and may enhance the effectiveness of antimicrobial agents, the resulting biological response of bacteria within the biofilms remains poorl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fmicb.2020.599407

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Oxford college:
Balliol College
Role:
Author
Publisher:
Frontiers Media
Journal:
Frontiers in Microbiology More from this journal
Volume:
11
Article number:
599407
Publication date:
2020-12-15
Acceptance date:
2020-11-23
DOI:
EISSN:
1664-302X
Pmid:
33384674
Language:
English
Keywords:
Pubs id:
1152594
Local pid:
pubs:1152594
Deposit date:
2021-09-13

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