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Plasma proteomics reveals markers of metabolic stress in HIV infected children with severe acute malnutrition

Abstract:

HIV infection affects up to 30% of children presenting with severe acute malnutrition (SAM) in Africa and is associated with increased mortality. Children with SAM are treated similarly regardless of HIV status, although mechanisms of nutritional recovery in HIV and/or SAM are not well understood. We performed a secondary analysis of a clinical trial and plasma proteomics data among children with complicated SAM in Kenya and Malawi. Compared to children with SAM without HIV (n = ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Role:
Author
ORCID:
0000-0001-8766-7470
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Name:
Wellcome Trust
Grant:
083579/Z/07/Z
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Name:
Medical Research Council
Grant:
MR/M007367/1
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Name:
Bill & Melinda Gates Foundation
Grant:
OPP1131320
UWSC11675
Publisher:
Springer Nature
Journal:
Scientific Reports More from this journal
Volume:
10
Issue:
1
Article number:
11235
Publication date:
2020-07-08
Acceptance date:
2020-06-17
DOI:
EISSN:
2045-2322
Pmid:
32641735
Language:
English
Keywords:
Pubs id:
1120249
Local pid:
pubs:1120249
Deposit date:
2020-09-16

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