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Electrosprayed genipin cross‐linked alginate–chitosan microcarriers for ex vivo expansion of mesenchymal stem cells

Abstract:

Mesenchymal stem cells (MSCs) are potential therapeutic candidates, owing to their ability to differentiate into several cell types. However, the gap between availability and demand of MSCs requires alternative expansion methods from 2D culture flasks. Microcarriers are a promising approach for MSC expansion due to their high surface area‐to‐volume ratio. However, current commercial microcarriers do not provide the highest cell yield due to low cell attachment efficiencies and difficulty in c...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/jbm.a.36539

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Oxford college:
Jesus College
Role:
Author
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
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Name:
China Regenerative Medicine International Limited
Publisher:
Wiley
Journal:
Journal of Biomedical Materials Research Part A More from this journal
Volume:
107
Issue:
1
Pages:
122-133
Publication date:
2018-09-26
Acceptance date:
2018-08-29
DOI:
ISSN:
1549-3296
Keywords:
Pubs id:
pubs:911165
UUID:
uuid:0a75c220-df78-4b8a-ae4d-99af96864721
Local pid:
pubs:911165
Source identifiers:
911165
Deposit date:
2018-08-30

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