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Utility of Plasmodium falciparum DNA from rapid diagnostic test kits for molecular analysis and whole genome amplification

Abstract:

Background

Rapid diagnostic tests (RDTs) have become the most common diagnostic tool for detection of Plasmodium falciparum malaria, in particular in remote areas. RDT blood spots provide a source of parasite DNA for molecular analysis. In this study, the utility of RDTs for molecular analysis and the performance of different methods for whole genome amplification were investigated.

Methods

Positive P. falciparum RDTs were collected f...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12936-020-03259-9

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-4704-9915
Thailand Science Research and Innovation (TSRI) More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
19
Article number:
193
Publication date:
2020-05-27
Acceptance date:
2020-05-15
DOI:
EISSN:
1475-2875
Pmid:
32460780
Language:
English
Keywords:
Pubs id:
1108940
Local pid:
pubs:1108940
Deposit date:
2020-06-16

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