Journal article
Volume‐localized measurement of oxygen extraction fraction in the brain using MRI
- Abstract:
-
PURPOSE:T2 -relaxation-under-spin-tagging (TRUST) is an MR technique for the non-invasive assessment of whole-brain cerebral oxygen extraction fraction (OEF), through measurement of the venous blood T2 relaxation time in the sagittal sinus. A key limitation of TRUST, however, is the lack of spatial specificity of the measurement. We sought to develop a modified TRUST sequence, selective localized TRUST (SL-TRUST), having sensitivity to venous blood T2 within a targeted brain region, and there...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ Medical Research Council (MRC) Centre for Doctoral Training in Biomedical Imaging
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Grant:
EP/L016052/1
Dunhill Medical Trust
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Oxford NIHR Biomedical Research Centre
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Engineering and Physical Sciences Research Council
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Magnetic Resonance in Medicine Journal website
- Volume:
- 82
- Issue:
- 4
- Pages:
- 1412-1423
- Publication date:
- 2019-05-27
- Acceptance date:
- 2019-05-01
- DOI:
- EISSN:
-
1522-2594
- ISSN:
-
0740-3194
- Pmid:
-
31131930
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1003448
- UUID:
-
uuid:0a1a420d-6c74-44af-b91a-3c37bea3f53a
- Local pid:
- pubs:1003448
- Source identifiers:
-
1003448
- Deposit date:
- 2019-05-30
Terms of use
- Copyright holder:
- O'Brien et al
- Copyright date:
- 2019
- Notes:
- © 2019 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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