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Journal article

Memo1-mediated tiling of radial glial cells facilitates cerebral cortical development

Abstract:: Polarized, non-overlapping, regularly spaced, tiled organization of radial glial cells (RGCs) serves as a framework to generate and organize cortical neuronal columns, layers, and circuitry. Here, we show that mediator of cell motility 1 (Memo1) is a critical determinant of radial glial tiling during neocortical development. Memo1 deletion or knockdown leads to hyperbranching of RGC basal processes and disrupted RGC tiling, resulting in aberrant radial unit assembly and neuronal layering. Mem...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Nakagawa, N., Plestant, C., Yabuno-Nakagawa, K., Li, J., Lee, J., Huang, C., Lee, A., Krupa, O., Adhikari, A., Thompson, S., Rhynes, T., Arevalo, V., Stein, J., Molnár, Z., Badache, A., & Anton, E. (2019). Memo1-mediated tiling of radial glial cells facilitates cerebral cortical development. Neuron, 103(5), 836–852.e5.

MLA Style

Nakagawa, N., et al. “Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development.” Neuron, vol. 103, no. 5, Elsevier, 2019, pp. 836–52.e5.

Chicago Style

Nakagawa, N, C Plestant, K Yabuno-Nakagawa, J Li, J Lee, C Huang, A Lee, et al. 2019. “Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development.” Neuron 103 (5): 836–52.e5.
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Publisher copy:: 10.1016/j.neuron.2019.05.049

Authors

+ Nakagawa, N More by this author

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+ Plestant, C More by this author

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+ Yabuno-Nakagawa, K More by this author

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+ Li, J More by this author

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+ Lee, J More by this author

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Funding

+ NINDS NIH HHS More from this funder

Grant:

R01 MH060929

+ NICHD NIH HHS More from this funder

Grant:

R01 HD098657

Bibliographic Details

Publisher:: Elsevier Publisher's website
Journal:: Neuron
Volume:: 103
Issue:: 5
Pages:: 836-852.e5
Publication date:: 2019-07-02
Acceptance date:: 2019-05-30
DOI:: 10.1016/j.neuron.2019.05.049
EISSN:: 1097-4199
ISSN:: 0896-6273
Pmid:: 31277925

Item Description

Language:: English
Keywords:: FFR
Pubs id:: pubs:1028737
UUID:: uuid:09f15c2f-745a-4b63-9d3f-0b367a84e778
Local pid:: pubs:1028737
Source identifiers:: 1028737
Deposit date:: 2019-12-18

Terms of use

Copyright date:: 2019

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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