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Journal article

Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system

Abstract:

Autocatalytic chemical reactions are widely studied as models of biological processes and to better understand the origins of life on earth. Minimal self-reproducing amphiphiles have been developed in this context, and as an approach to de novo ‘bottom-up’ synthetic protocells. How chemicals come together to produce living systems remains poorly understood, despite much experimentation and speculation. Here, we use ultrasensitive label-free optical microscopy to visualize the spontaneous emer...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1073/pnas.1602363113

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More from this funder
Name:
European Research Council
Funding agency for:
Kukura, P
Fletcher, S
Grant:
EP/M025241/1
EP/M025241/1
More from this funder
Name:
Engineering and Physical Sciences Research Council
Funding agency for:
Bissette, A
Fletcher, S
Kukura, P
Grant:
EP/M025241/1
EP/M025241/1
More from this funder
Name:
Consejo Nacional de Ciencia y Tecnología
Grant:
213546
Publisher:
National Academy of Science
Journal:
Proceedings of the National Academy of Sciences of USA More from this journal
Volume:
113
Issue:
40
Pages:
11122–11126
Publication date:
2016-08-01
Acceptance date:
2016-08-02
DOI:
ISSN:
1091-6490
Keywords:
Pubs id:
pubs:637006
UUID:
uuid:09cad8af-0bc2-49dc-aa98-3f019a8e06ce
Local pid:
pubs:637006
Source identifiers:
637006
Deposit date:
2016-08-02

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