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Effects of detergent micelles on lipid binding to proteins in electrospray ionization mass spectrometry

Abstract:

A wide variety of biological processes rely upon interactions between proteins and lipids, ranging from molecular transport to the organization of the cell membrane. It was recently established that electrospray ionization mass spectrometry (ESI-MS) is capable of capturing transient interactions between membrane proteins and their lipid environment, and a detailed understanding of the underlying processes is therefore of high importance. Here, we apply ESI-MS to investigate the factors that g...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1021/acs.analchem.7b00922

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Department:
Oxford
Role:
Author
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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
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Institution:
University of Oxford
Oxford college:
Exeter College
Role:
Author
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Name:
European Research Council
Funding agency for:
Landreh, M
Robinson, C
Grant:
Marie Curie early career development grant
Program grant (MR/N020413/1
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Name:
Medical Research Council
Funding agency for:
Robinson, C
Grant:
Program grant (MR/N020413/1
More from this funder
Name:
Wellcome Trust
Funding agency for:
Robinson, C
Grant:
Program grant (MR/N020413/1
Publisher:
American Chemical Society
Journal:
Analytical Chemistry More from this journal
Volume:
89
Issue:
14
Pages:
7425–7430
Publication date:
2017-07-03
Acceptance date:
2017-06-19
DOI:
EISSN:
1520-6882
ISSN:
0003-2700
Language:
English
Pubs id:
pubs:707981
UUID:
uuid:09c9f481-c7df-42d7-982d-dee3f9b30bd0
Local pid:
pubs:707981
Deposit date:
2017-07-17

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