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Journal article

Blood-based ATN biomarkers of Alzheimer’s disease: a meta-analysis

Abstract:

Background: The Amyloid Tau Neurodegeneration (ATN) framework was proposed to define the biological state underpinning Alzheimer’s disease (AD). Blood-based biomarkers offer a scalable alternative to the costly and invasive currently available biomarkers.

Objective: In this meta-analysis we sought to assess the diagnostic performance of plasma amyloid (Aβ40, Aβ42, Aβ42/40 ratio), tangle (p-tau181), and neurodegeneration (total tau [t-tau], neurofi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3233/JAD-200900

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0001-6813-8493
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0003-1752-0419
Publisher:
IOS Press Publisher's website
Journal:
Journal of Alzheimer's Disease Journal website
Volume:
79
Issue:
1
Pages:
177-195
Publication date:
2021-01-05
Acceptance date:
2020-10-15
DOI:
ISSN:
1387-2877
Language:
English
Keywords:
Pubs id:
1137915
Local pid:
pubs:1137915
Deposit date:
2020-10-16

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