Journal article
Stochastic Sensing of Chloride Anions Using an α‐Hemolysin Pore with a semiaza ‐Bambusuril Adapter
- Abstract:
- Pores containing molecular adapters provide internal selective binding sites, thereby allowing the stochastic sensing of analytes. Herein, we demonstrate that semiaza‐bambusuril (BU) acts as a non‐covalent molecular adapter when lodged within the lumen of the wild‐type α‐hemolysin (WT‐αHL) protein pore. Because the bambusurils are recognized as anion receptors, the anion binding site within the adapter‐nanopore complex allows the detection of chloride anions, thus converting a non‐selective pore into an anion sensor.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of Record, Version of record, pdf, 1017.1KB, Terms of use)
-
- Publisher copy:
- 10.1002/anie.202406719
Authors
- Publisher:
- Wiley
- Journal:
- Angewandte Chemie International Edition More from this journal
- Article number:
- e202406719
- Publication date:
- 2024-08-29
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851 and 1521-3773
- Language:
-
English
- Keywords:
- Source identifiers:
-
2224619
- Deposit date:
-
2024-08-30
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.
If you are the owner of this record, you can report an update to it here: Report update to this record