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Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

Abstract:

Small fibres in the skin are vulnerable to damage in metabolic or toxic conditions such as diabetes mellitus or chemotherapy resulting in small fibre neuropathy and associated neuropathic pain (NP). Whether injury to the most distal portion of sensory small fibres due to a primary dermatological disorder can cause NP is still unclear. Recessive Dystrophic Epidermolysis Bullosa, (RDEB) is a rare condition in which mutations of proteins of the dermo-epidermal junction lead to cycles of blisteri...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/brain/awx069

Authors


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Name:
Wellcome Trust
Funding agency for:
Bennett, D
Grant:
095698z/11/z
202747/z/16/z
Publisher:
Oxford University Press
Journal:
Brain More from this journal
Volume:
140
Issue:
5
Pages:
1238-1251
Publication date:
2017-01-01
Acceptance date:
2017-01-20
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Keywords:
Pubs id:
pubs:672274
UUID:
uuid:096f6267-783e-4d60-9489-9dddcd772eec
Local pid:
pubs:672274
Source identifiers:
672274
Deposit date:
2017-01-21

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