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Total fatty acid analysis of human blood samples in one minute by high-resolution mass spectrometry

Abstract:

Total fatty acid analysis is a routine method in many areas, including lipotyping of individuals in personalized medicine, analysis of foodstuffs, and optimization of oil production in biotechnology. This analysis is commonly done by converting fatty acyl (FA) chains of intact lipids into FA methyl esters (FAMEs) and monitoring these by gas-chromatography (GC)-based methods, typically requiring at least 15 min of analysis per sample. Here, we describe a novel method that supports fast, precis...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/biom9010007

Authors


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Role:
Author
ORCID:
0000-0003-4886-0811
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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
ORCID:
0000-0002-2648-6526
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Role:
Author
ORCID:
0000-0003-4963-0276
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Name:
VILLUM Center for Bioanalytical Sciences
Grant:
VKR023179
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Name:
University of Southern Denmark
Grant:
SDU2020
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Name:
Danish Council for Strategic Research
Grant:
11-116196
Publisher:
MDPI
Journal:
Biomolecules More from this journal
Volume:
9
Issue:
1
Article number:
7
Publication date:
2018-12-27
Acceptance date:
2018-12-17
DOI:
EISSN:
2218-273X
ISSN:
2218-273X
Pmid:
30591667
Language:
English
Keywords:
Pubs id:
pubs:959249
UUID:
uuid:0950d9ef-356f-4061-9182-5e0723eef7a7
Local pid:
pubs:959249
Source identifiers:
959249
Deposit date:
2019-02-12

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