Journal article icon

Journal article

Left ventricular diastolic myocardial stiffness and end-diastolic myofibre stress in human heart failure using personalised biomechanical analysis

Abstract:

Understanding the aetiology of heart failure with preserved (HFpEF) and reduced (HFrEF) ejection fraction requires knowledge of biomechanical factors such as diastolic myocardial stiffness and stress. Cine CMR images and intra-ventricular pressure recordings were acquired in 8 HFrEF, 11 HFpEF and 5 control subjects. Diastolic myocardial stiffness was estimated using biomechanical models and found to be greater in HFrEF (6.4 ± 1.2 kPa) than HFpEF (2.7 ± 0.6 kPa, p 

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1007/s12265-018-9816-y

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Computer Science
Department:
Unknown
Role:
Author
ORCID:
0000-0001-5325-909X
More from this funder
Name:
Health Research Council of New Zealand
Grant:
17/608
Publisher:
Springer Verlag
Journal:
Journal of Cardiovascular Translational Research More from this journal
Volume:
11
Issue:
4
Pages:
346–356
Publication date:
2018-07-11
Acceptance date:
2018-06-26
DOI:
EISSN:
1937-5395
ISSN:
1937-5387
Keywords:
Pubs id:
pubs:930306
UUID:
uuid:08cf46be-f2ab-49a1-a88b-d4304f38ed72
Local pid:
pubs:930306
Source identifiers:
930306
Deposit date:
2018-10-22

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP