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Journal article

Genetic variation at 16q24.2 is associated with small vessel stroke

Abstract:

OBJECTIVE: Genome-wide association studies (GWAS) have been successful at identifying associations with stroke and stroke subtypes, but have not yet identified any associations solely with small vessel stroke (SVS). SVS comprises one quarter of all ischemic stroke and is a major manifestation of cerebral small vessel disease, the primary cause of vascular cognitive impairment. Studies across neurological traits have shown that younger-onset cases have an increased genetic burden. We levera...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ana.24840

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Publisher:
Wiley
Journal:
Annals of Neurology More from this journal
Volume:
81
Issue:
3
Pages:
383-394
Publication date:
2017-03-25
Acceptance date:
2017-12-03
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
Language:
English
Keywords:
Pubs id:
pubs:667629
UUID:
uuid:08c00038-936e-4fbb-8f05-4376ad858dd8
Local pid:
pubs:667629
Source identifiers:
667629
Deposit date:
2017-07-31

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