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Journal article

Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation

Abstract:
The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, some other mechanism must drive their development. Here we consider models for deformation of the interphase NE, together with the evidence for their potential roles in NR formation.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1080/19491034.2016.1252893

Authors


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Department:
Oxford, MSD, Pathology Dunn School
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Department:
Oxford, MSD, Pathology Dunn School
Edward Penley Abraham Trust More from this funder
Publisher:
Taylor & Francis Publisher's website
Journal:
Nucleus Journal website
Volume:
8
Issue:
1
Pages:
34-45
Publication date:
2016-10-31
Acceptance date:
2016-10-19
DOI:
EISSN:
1949-1042
ISSN:
1949-1034
Pubs id:
pubs:656006
URN:
uri:07ad9e7f-0f5e-40db-8971-cbddc17b4ab7
UUID:
uuid:07ad9e7f-0f5e-40db-8971-cbddc17b4ab7
Local pid:
pubs:656006

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