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Journal article

Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation

Abstract:
The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, some other mechanism must drive their development. Here we consider models for deformation of the interphase NE, together with the evidence for their potential roles in NR formation.
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More from this funder
Name:
Biotechnology and Biological Sciences Research Council
Grant:
BBSRC studentship
BB/L002159/1
More from this funder
Name:
Edward Penley Abraham Trust
Publisher:
Taylor and Francis
Journal:
Nucleus More from this journal
Volume:
8
Issue:
1
Pages:
34-45
Publication date:
2016-10-31
Acceptance date:
2016-10-19
DOI:
EISSN:
1949-1042
ISSN:
1949-1034
Keywords:
Pubs id:
pubs:656006
UUID:
uuid:07ad9e7f-0f5e-40db-8971-cbddc17b4ab7
Local pid:
pubs:656006
Source identifiers:
656006
Deposit date:
2016-11-01

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