Journal article
Initial identification of a blood-based chromosome conformation signature for aiding in the diagnosis of amyotrophic lateral sclerosis
- Abstract:
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Background The identification of blood-based biomarkers specific to the diagnosis of amyotrophic lateral sclerosis (ALS) is an active field of academic and clinical research. While inheritance studies have advanced the field, a majority of patients do not have a known genetic link to the disease, making direct sequence-based genetic testing for ALS difficult. The ability to detect biofluid-based epigenetic changes in ALS would expand the relevance of using genomic information... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.1MB)
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- Publisher copy:
- 10.1016/j.ebiom.2018.06.015
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Authors
Funding
+ Medical Research Council
More from this funder
Funding agency for:
Turner, M
Grant:
Lady Edith Wolfson Senior Clinical Fellowship (MR/K01014X/1
+ Motor Neurone Disease Association
More from this funder
Funding agency for:
Turner, M
Grant:
Lady Edith Wolfson Senior Clinical Fellowship (MR/K01014X/1
Oxford BioDynamics
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Innovate UK
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 33
- Pages:
- 169-184
- Publication date:
- 2018-06-23
- Acceptance date:
- 2018-06-12
- DOI:
- ISSN:
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2352-3964
- Pmid:
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29941342
- Source identifiers:
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859936
Item Description
- Language:
- English
- Pubs id:
-
pubs:859936
- UUID:
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uuid:0707df80-621e-42ca-ae6b-da1594d883cb
- Local pid:
- pubs:859936
- Deposit date:
- 2018-10-04
Terms of use
- Copyright holder:
- Salter et al
- Copyright date:
- 2018
- Notes:
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Copyright © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license
(http://creativecommons.org/licenses/by-nc-nd/4.0/).
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