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Journal article

High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine.

Abstract:

Background

Neisseria meningitidis is a globally important cause of meningitis and septicaemia. Twelve capsular groups of meningococci are known, and quadrivalent vaccines against four of these (A, C, W and Y) are available as plain-polysaccharide and protein-polysaccharide conjugate vaccines. Here we apply contemporary methods to describe B-cell responses to meningococcal polysaccharide and conjugate vaccines.

Methods

Twenty adults were randomly assigned to receiv...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Magdalen College
Role:
Author
More from this funder
Name:
Oxford Martin School
Funding agency for:
Pollard, A
Grant:
James Martin Senior Fellow
More from this funder
Name:
Jenner Institute
Funding agency for:
Pollard, A
Grant:
James Martin Senior Fellow
More from this funder
Name:
Seventh Framework Programme
Funding agency for:
O'Connor, D
Grant:
279185
More from this funder
Name:
National Institute for Health Research
Funding agency for:
Clutterbuck, E
Snape, M
Kelly, D
Publisher:
BioMed Central
Journal:
Genome Medicine More from this journal
Volume:
9
Issue:
1
Pages:
11
Publication date:
2017-01-01
Acceptance date:
2017-01-05
DOI:
ISSN:
1756-994X
Language:
English
Keywords:
Pubs id:
pubs:675167
UUID:
uuid:070022b5-4ccc-4764-98ee-a944bc66010a
Local pid:
pubs:675167
Source identifiers:
675167
Deposit date:
2017-02-07

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