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Prophylactic antibiotics for the prevention of infection following operative vaginal delivery (ANODE): study protocol for a randomised controlled trial

Abstract:

Background: Sepsis is one of the most important causes of maternal death and severe morbidity worldwide. Studies conducted both in the UK and US have documented an additional risk associated with operative vaginal delivery. However, a Cochrane review, updated in 2017, identified only one small trial of prophylactic antibiotics following operative vaginal delivery, which included a total of 393 women. Given the small size of that trial, it recommended that further robust evidence is needed....

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-018-2787-0

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author
ORCID:
0000-0002-1984-4575
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; NPEU
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; NPEU
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; NPEU
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; NPEU
Role:
Author
More from this funder
Name:
National Institute for Health Research
Grant:
13/96/07
Publisher:
BioMed Central
Journal:
Trials More from this journal
Volume:
19
Article number:
395
Publication date:
2018-07-24
Acceptance date:
2018-07-04
DOI:
EISSN:
1745-6215
Pubs id:
pubs:866891
UUID:
uuid:0695ae5f-249c-4263-b813-232bd2f94d30
Local pid:
pubs:866891
Source identifiers:
866891
Deposit date:
2018-07-19

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