- Abstract:
-
Chronic sleep disturbances, associated with cardio-metabolic diseases, psychiatric disorders and all-cause mortality1,2, affect 25-30% of adults worldwide. While environmental factors contribute importantly to self-reported habitual sleep duration and disruption, these traits are heritable4-9, and gene identification should improve our understanding of sleep function, mechanisms linking sleep to disease, and development of novel therapies. We report single and multi-trait genome-wide associat...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 2.3MB)
-
- Publisher copy:
- 10.1038/ng.3749
-
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- Grant:
- R01DK107859 (RS), R21HL121728 (RS), F32DK102323 (JML), 413 R01HL113338 (JML, SR and RS), R01DK102696 (RS and FS), R01DK105072 (RS and FS), 414 T32HL007567(JL), HG003054 (XZ)
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 49
- Pages:
- 274–281
- Publication date:
- 2016-12-19
- Acceptance date:
- 2016-11-25
- DOI:
- EISSN:
-
1546-1718
- ISSN:
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1061-4036
- Pubs id:
-
pubs:662099
- URN:
-
uri:067bf112-a954-466d-8df0-f57debf75b52
- UUID:
-
uuid:067bf112-a954-466d-8df0-f57debf75b52
- Local pid:
- pubs:662099
- Keywords:
- Copyright holder:
- Lane et al.
- Copyright date:
- 2016
- Notes:
- © 2017 Author(s); published by Macmillan Publishers Limited, part of Springer Nature. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: [10.1038/ng.3749]
Journal article
Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
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