- Abstract:
-
We identified a patient with severe inherited erythromelalgia secondary to an L858F mutation in the voltage-gated sodium channel Na(v)1.7. The patient reported severe ongoing foot pain, which was exquisitely sensitive to limb cooling. We confirmed this heat hypersensitivity using quantitative sensory testing. Additionally, we employed a novel perfusion imaging technique in a simple block design to assess her baseline erythromelalgia pain vs cooling relief. Robust activations of key pain, pain...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.pain.2011.12.012
-
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- Journal:
- Pain
- Volume:
- 153
- Issue:
- 5
- Pages:
- 1122-1127
- Publication date:
- 2012-05-05
- DOI:
- EISSN:
-
1872-6623
- ISSN:
-
0304-3959
- URN:
-
uuid:05cc8809-6e08-450b-92cc-48bbcae163b0
- Source identifiers:
-
313037
- Local pid:
- pubs:313037
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Imaging the neural correlates of neuropathic pain and pleasurable relief associated with inherited erythromelalgia in a single subject with quantitative arterial spin labelling.
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