Journal article icon

Journal article

Imaging the neural correlates of neuropathic pain and pleasurable relief associated with inherited erythromelalgia in a single subject with quantitative arterial spin labelling.

Abstract:

We identified a patient with severe inherited erythromelalgia secondary to an L858F mutation in the voltage-gated sodium channel Na(v)1.7. The patient reported severe ongoing foot pain, which was exquisitely sensitive to limb cooling. We confirmed this heat hypersensitivity using quantitative sensory testing. Additionally, we employed a novel perfusion imaging technique in a simple block design to assess her baseline erythromelalgia pain vs cooling relief. Robust activations of key pain, pain...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.pain.2011.12.012

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Expand authors...
Journal:
Pain
Volume:
153
Issue:
5
Pages:
1122-1127
Publication date:
2012-05-01
DOI:
EISSN:
1872-6623
ISSN:
0304-3959
Source identifiers:
313037
Language:
English
Keywords:
Pubs id:
pubs:313037
UUID:
uuid:05cc8809-6e08-450b-92cc-48bbcae163b0
Local pid:
pubs:313037
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP