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Heritable components of the human fecal microbiome are associated with visceral fat

Abstract:
Background Variation in the human fecal microbiota has previously been associated with body mass index (BMI). Although obesity is a global health burden, the accumulation of abdominal visceral fat is the specific cardio-metabolic disease risk factor. Here, we explore links between the fecal microbiota and abdominal adiposity using body composition as measured by dual-energy X-ray absorptiometry in a large sample of twins from the TwinsUK cohort, comparing fecal 16S rRNA diver... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0002-3227-380X
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Sub department:
KIR
Department:
KIR
Role:
Author
ORCID:
0000-0002-7891-6217
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Role:
Author
ORCID:
0000-0002-6938-4933
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Name:
European Research Council
Grant:
250157
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Name:
European Union
Grant:
FP7/2007-2013
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Name:
National Institutes of Health
Grant:
RO1 DK093595
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Name:
National Institute for Health Research
Publisher:
BioMed Central
Journal:
Genome Biology More from this journal
Volume:
17
Issue:
1
Article number:
189
Publication date:
2016-09-26
Acceptance date:
2016-08-31
DOI:
ISSN:
1474-760X
Pmid:
27666579
Language:
English
Keywords:
Pubs id:
pubs:904942
UUID:
uuid:05a6a476-31b9-4af8-858f-f120c52db813
Local pid:
pubs:904942
Source identifiers:
904942
Deposit date:
2018-09-03

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