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Journal article

DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility

Abstract:
Aim of the study A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as ‘epigenetic clock’, has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based biomarkers for risk stratification. Methods Here, we prof... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ejca.2017.01.014

Authors


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Role:
Author
ORCID:
0000-0003-3102-3603
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Role:
Author
ORCID:
0000-0001-6045-2103
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Name:
European Commission
Grant:
Seventh Framework Programme (FP7 Exposomics) (308610-2) Translational Cancer Research (TRANSCAN) (TRANS201301184) Framework
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Name:
Institut National du Cancer
Grant:
16491
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Name:
Cancer Research UK
Grant:
16491
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Name:
Regional Government of Asturias
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Name:
Fondation Association pour la Recherche contre le Cancer
Publisher:
Elsevier
Journal:
European Journal of Cancer More from this journal
Volume:
75
Pages:
299-307
Publication date:
2017-02-28
Acceptance date:
2017-01-20
DOI:
EISSN:
1879-0852
ISSN:
0959-8049
Pmid:
28259012
Language:
English
Keywords:
Pubs id:
pubs:685316
UUID:
uuid:057c08c0-5cac-488a-915b-c87b66d95cf6
Local pid:
pubs:685316
Source identifiers:
685316
Deposit date:
2018-11-27

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