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Journal article

The adaptive immune response to cardiac injury—the true roadblock to effective regenerative therapies?

Abstract:

The regenerative capacity of adult human tissues and organs is limited, but recent developments have seen the advent of promising new technologies for regenerative therapy. The human heart is of particular interest for regenerative medicine, as cardiac tissue damage is repaired by the formation of rigid scar tissue, which causes inevitable structural changes and progressive functional decline leading to heart failure. Cardiac regenerative medicine aims to prevent scar formation or replace exi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41536-017-0022-3

Authors


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Institution:
University of Oxford
Oxford college:
Trinity College
Role:
Author
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Funding agency for:
Harding, SE
Grant:
RM/13/1/30157
Publisher:
Nature Publishing Group Publisher's website
Journal:
npj Regenerative Medicine Journal website
Volume:
2
Issue:
1
Pages:
1-5
Publication date:
2017-06-19
Acceptance date:
2017-05-17
DOI:
ISSN:
2057-3995
Pubs id:
pubs:720347
UUID:
uuid:056f381a-e863-49a4-ad57-f9a5b74530fb
Local pid:
pubs:720347
Source identifiers:
720347
Deposit date:
2017-08-17

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