Journal article
Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate-amodiaquine fixed dose combination or artemether-lumefantrine in Liberia
- Abstract:
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Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug resistance can provide a useful tool to track resistance and guide treatment policy as well as an in-depth understanding of the development and spread of resistance.The role of P. falciparum molecula...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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(pdf, 1.0MB)
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- Publisher copy:
- 10.1186/s12936-016-1503-3
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Authors
Funding
Drugs for Neglected Diseases initiative
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria journal Journal website
- Volume:
- 15
- Issue:
- 452
- Pages:
- 1-6
- Publication date:
- 2016-09-05
- Acceptance date:
- 2016-08-26
- DOI:
- ISSN:
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1475-2875
- Pubs id:
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pubs:642227
- URN:
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uri:0560574b-a45b-4e3b-be83-ffe5365bb34c
- UUID:
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uuid:0560574b-a45b-4e3b-be83-ffe5365bb34c
- Local pid:
- pubs:642227
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- © Otienoburu, et al 2016
- Copyright date:
- 2016
- Notes:
- This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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