Journal article icon

Journal article

Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate-amodiaquine fixed dose combination or artemether-lumefantrine in Liberia

Abstract:

Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug resistance can provide a useful tool to track resistance and guide treatment policy as well as an in-depth understanding of the development and spread of resistance.The role of P. falciparum molecula...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1186/s12936-016-1503-3

Authors


Otienoburu, SD More by this author
Maïga-Ascofaré, O More by this author
Schramm, B More by this author
Jullien, V More by this author
Expand authors...
Drugs for Neglected Diseases initiative More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria journal Journal website
Volume:
15
Issue:
452
Pages:
1-6
Publication date:
2016-09-05
Acceptance date:
2016-08-26
DOI:
ISSN:
1475-2875
Pubs id:
pubs:642227
URN:
uri:0560574b-a45b-4e3b-be83-ffe5365bb34c
UUID:
uuid:0560574b-a45b-4e3b-be83-ffe5365bb34c
Local pid:
pubs:642227

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP