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The impact of HCV therapy in a high HIV-HCV prevalence population: A modeling study on people who inject drugs in Ho Chi Minh City, Vietnam

Abstract:

BACKGROUND: Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) coinfection is a major global health problem especially among people who inject drugs (PWID), with significant clinical implications. Mathematical models have been used to great effect to shape HIV care, but few have been proposed for HIV/HCV. METHODS: We constructed a deterministic compartmental ODE model that incorporated layers for HIV disease progression, HCV disease progression and PWID demography. Antiretroviral ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0177195

Authors


Birger, RB More by this author
More by this author
Department:
Oxford, MSD, NDM, Tropical Medicine
Kouyos, RD More by this author
Grenfell, BT More by this author
Hallett, TB More by this author
More from this funder
Funding agency for:
Le, T
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
12
Issue:
5
Pages:
Article: e0177195
Publication date:
2017-05-11
DOI:
ISSN:
1932-6203
Pubs id:
pubs:695867
URN:
uri:051505ec-67d2-4cda-b395-35f8ff08b794
UUID:
uuid:051505ec-67d2-4cda-b395-35f8ff08b794
Local pid:
pubs:695867
Language:
English

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