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Randomised controlled trial to compare the diagnostic yield of positron emission tomography CT (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy (TARGET trial)

Abstract:
Introduction Pleural malignancy, particularly malignant pleural mesothelioma (MPM) is increasing in incidence due to the long latency period from exposure to asbestos to development of the disease. MPM can be challenging to diagnose. For patients presenting without a pleural effusion, CT-guided biopsy remains the primary choice of biopsy, but the diagnostic sensitivity of this investigation is 70%–75%. Therefore, a proportion of patients will go on to require further biopsies... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjresp-2017-000270

Authors


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Role:
Author
ORCID:
0000-0002-0060-9671
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0003-1195-1680
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Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Open Respiratory Research Journal website
Volume:
5
Pages:
e000270
Publication date:
2018-01-01
Acceptance date:
2018-01-01
DOI:
EISSN:
2052-4439
Pmid:
29616141
Source identifiers:
831604
Language:
English
Keywords:
Pubs id:
pubs:831604
UUID:
uuid:049dc7a6-ef24-4f20-b9c4-b296285c729c
Local pid:
pubs:831604
Deposit date:
2018-09-05

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