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Randomised controlled trial to compare the diagnostic yield of positron emission tomography CT (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy (TARGET trial)

Abstract:
Introduction Pleural malignancy, particularly malignant pleural mesothelioma (MPM) is increasing in incidence due to the long latency period from exposure to asbestos to development of the disease. MPM can be challenging to diagnose. For patients presenting without a pleural effusion, CT-guided biopsy remains the primary choice of biopsy, but the diagnostic sensitivity of this investigation is 70%–75%. Therefore, a proportion of patients will go on to require further biopsies... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1136/bmjresp-2017-000270

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ORCID:
0000-0002-0060-9671
Underwood, W More by this author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
ORCID:
0000-0003-1195-1680
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Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Open Respiratory Research Journal website
Volume:
5
Pages:
e000270
Publication date:
2018-01-05
DOI:
EISSN:
2052-4439
Pubs id:
pubs:831604
URN:
uri:049dc7a6-ef24-4f20-b9c4-b296285c729c
UUID:
uuid:049dc7a6-ef24-4f20-b9c4-b296285c729c
Local pid:
pubs:831604
Language:
English
Keywords:

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