Journal article : Review
Primary, post-primary and non-specific immunoglobulin M responses in HCV infection
- Abstract:
-
Delayed and variable antibody responses to HCV make it difficult to diagnose acute HCV infection reliably. Immunoglobulin (Ig)M and IgG anti-HCV may be observed simultaneously as disease persists. IgM plays a key role in mixed cryoglobulinemia (MC), an immune complex disease strongly associated with persistent HCV infection. In MC, clonal or oligoclonal IgM rheumatoid factors facilitate the deposition of immune complexes in small blood vessels and tissue, leading to inflammation, complement a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
NIAID NIH HHS
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Bibliographic Details
- Publisher:
- International Medical Press Publisher's website
- Journal:
- Antiviral Therapy Journal website
- Volume:
- 17
- Issue:
- 7 Pt B
- Pages:
- 1449-1452
- Publication date:
- 2012-12-07
- Acceptance date:
- 2012-04-17
- DOI:
- EISSN:
-
2040-2058
- ISSN:
-
1359-6535
- Pmid:
-
23322600
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
426214
- Local pid:
- pubs:426214
- Deposit date:
- 2022-01-17
Terms of use
- Copyright holder:
- International Medical Press
- Copyright date:
- 2012
- Rights statement:
- © 2012 International Medical Press
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