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Journal article

Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies

Abstract:

Colorectal cancer (CRC) biopsies underpin accurate diagnosis, but are also relevant for patient stratification in molecularly-guided clinical trials. The consensus molecular subtypes (CMSs) and colorectal cancer intrinsic subtypes (CRISs) transcriptional signatures have potential clinical utility for improving prognostic/predictive patient assignment. However, their ability to provide robust classification, particularly in pretreatment biopsies from multiple regions or at different time point...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/path.5051

Authors


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Role:
Author
ORCID:
0000-0002-6440-0260
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Name:
Medical Research Council
Grant:
HDR-6003
MR/M016587/1
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Name:
Cancer Research UK
Grant:
15954
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Name:
Public Health Agency
Grant:
SPI/3315/06
Publisher:
Wiley
Journal:
Journal of Pathology More from this journal
Volume:
245
Issue:
1
Pages:
19-28
Publication date:
2018-03-27
Acceptance date:
2018-01-31
DOI:
EISSN:
1096-9896
ISSN:
0022-3417
Pmid:
29412457
Language:
English
Keywords:
Pubs id:
pubs:823372
UUID:
uuid:04585253-91b5-4bf0-bd6e-dcc193304ea2
Local pid:
pubs:823372
Source identifiers:
823372
Deposit date:
2019-06-19

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