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Infectivity of chronic malaria infections and its consequences for control and elimination

Abstract:

Assessing the importance of targeting the chronic Plasmodium falciparum malaria reservoir is pivotal as the world moves toward malaria eradication. Through the lens of a mathematical model, we show how, for a given malaria prevalence, the relative infectivity of chronic individuals determines what intervention tools are predicted be the most effective. Crucially, in a large part of the parameter space where elimination is theoretically possible, it can be achieved solely through improved case...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/cid/ciy055

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
ORCID:
0000-0002-5355-0562
Gomes, MGM More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
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Bill and Melinda Gates Foundation More from this funder
Mahidol University More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Volume:
67
Issue:
2
Pages:
295–302
Publication date:
2018-05-10
Acceptance date:
2018-02-07
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Pubs id:
pubs:852984
URN:
uri:042db4c6-095f-46ea-ab3d-98b2f5672ebb
UUID:
uuid:042db4c6-095f-46ea-ab3d-98b2f5672ebb
Local pid:
pubs:852984

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