Journal article
Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles
- Abstract:
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Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease outcome have been identified. We hypothesized that macrophages from individuals with different clinical manifestations of Mycobacterium tuberculosis (Mtb) infection would have distinct gene expression profiles and that polymorphisms in these genes may also be associated with susceptibility to TB. We measured gene expression levels of >38,500 genes from ex vivo Mtb...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 259.1KB)
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- Publisher copy:
- 10.1371/journal.ppat.1000229
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Authors
Funding
+ Agency for Science Technology and Research, Singapore
More from this funder
Funding agency for:
Hibberd, M
+ Agency for Science Technology and Research, Singapore
More from this funder
Funding agency for:
Seielstad, M
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Bibliographic Details
- Publisher:
- PLoS Publisher's website
- Journal:
- PLoS Pathogens Journal website
- Volume:
- 4
- Issue:
- 12
- Article number:
- e1000229
- Publication date:
- 2008-12-05
- Acceptance date:
- 2008-11-05
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
- Pmid:
-
19057661
- Source identifiers:
-
92797
Item Description
- Keywords:
- Pubs id:
-
pubs:92797
- UUID:
-
uuid:0426f081-e8e7-4eba-be60-c570ee245422
- Local pid:
- pubs:92797
- Deposit date:
- 2017-05-03
Terms of use
- Copyright holder:
- Thuong et al
- Copyright date:
- 2008
- Notes:
- © 2008 Thuong et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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