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A world without bacterial meningitis: how genomic epidemiology can inform vaccination strategy

Abstract:

Bacterial meningitis remains an important cause of global morbidity and mortality. Although effective vaccinations exist and are being increasingly used worldwide, bacterial diversity threatens their impact and the ultimate goal of eliminating the disease. Through genomic epidemiology, we can appreciate bacterial population structure and its consequences for transmission dynamics, virulence, antimicrobial resistance, and development of new vaccines. Here, we review what we have learned throug...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.12688/f1000research.13793.1

Authors


More by this author
Institution:
University of Oxford
Division:
Maths, Physical & Life Sciences
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Oxford college:
Hertford College
Role:
Author
ORCID:
0000-0001-6321-5138
More from this funder
Funding agency for:
Maiden, M
Rodrigues, C
Grant:
104992/Z/14/Z
109031/Z15/Z
Publisher:
F1000Research Publisher's website
Journal:
F1000Research Journal website
Volume:
7
Pages:
401
Publication date:
2018-03-27
Acceptance date:
2018-03-27
DOI:
ISSN:
2046-1402
Pmid:
29636909
Language:
English
Keywords:
Pubs id:
pubs:835585
UUID:
uuid:03fd6e53-6c60-4ac8-870c-cc871d2d3083
Local pid:
pubs:835585
Source identifiers:
835585
Deposit date:
2018-07-24

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