Journal article
Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer
- Abstract:
-
Intratumoural heterogeneity (ITH) contributes to local recurrence following radiotherapy in prostate cancer. Recent studies also show that ecological interactions between heterogeneous tumour cell populations can lead to resistance in chemotherapy. Here, we evaluated whether interactions between heterogenous populations could impact growth and response to radiotherapy in prostate cancer. Using mixed 3D cultures of parental and radioresistant populations from two prostate cancer cell lines and...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Communications Biology Journal website
- Volume:
- 4
- Issue:
- 1
- Article number:
- 6
- Publication date:
- 2021-01-04
- Acceptance date:
- 2020-11-24
- DOI:
- EISSN:
-
2399-3642
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1156308
- Local pid:
- pubs:1156308
- Deposit date:
- 2021-01-15
Terms of use
- Copyright holder:
- Paczkowski et al.
- Copyright date:
- 2021
- Rights statement:
- ©2021 The Authors.
- Notes:
- Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record