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Journal article

Incidence of primary mitochondrial disease in children younger than 2 years presenting with acute liver failure

Abstract:

Background: Mitochondrial liver disease (MLD), and in particular mitochondrial DNA (mtDNA) depletion syndrome (MDS) is an important cause of acute liver failure (ALF) in infancy. Early and accurate diagnosis is important because liver transplantation (LT) is often contraindicated. It is unclear which methods are the best to diagnose MLD in the setting of ALF.

Objective: The aim of the study was to determine the incidence of MLD in children younger t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1097/MPG.0000000000001345

Authors


Great Ormond Street Hospital Children’s Charity More from this funder
UK NHS Highly Specialized 'Rare Mitochondrial Disorders of Adults and Children' Service More from this funder
Publisher:
Wolters Kluwer Publisher's website
Journal:
Journal of Pediatric Gastroenterology and Nutrition Journal website
Volume:
63
Issue:
6
Pages:
592-597
Publication date:
2016-12-01
Acceptance date:
2016-07-21
DOI:
EISSN:
1536-4801
ISSN:
0277-2116
Pmid:
27482763
Keywords:
Pubs id:
pubs:720815
UUID:
uuid:03c68b87-453f-4f18-b8b6-48801eb69fc8
Local pid:
pubs:720815
Source identifiers:
720815
Deposit date:
2018-01-30

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